What is Wernicke-Korsakoff Syndrome?
Wernicke-Korsakoff Syndrome is a condition associated with long-term alcohol use that can lead to significant neurological problems. The syndrome occurs as a result of vitamin B1 deficiency (thiamine deficiency) and can cause serious impairment of brain function.
Memory loss and cognitive problems
Wernicke-Korsakoff Syndrome is actually the name of a syndrome that is the combination of two different conditions. Firstly, there is an acute condition known as Wernicke encephalopathy. This condition is caused by a sudden and severe thiamine (vitamin B1) deficiency and can quickly lead to serious damage to the brain.
If left untreated, Wernicke encephalopathy can develop into a more chronic condition known as Korsakoff psychosis

Distortion of perception of time and space
Diagnosis of Wernicke-Korsakoff Syndrome is usually based on clinical symptoms and the patient’s history of alcohol consumption. Diagnosis may also be supported by medical examination, blood tests, and brain imaging techniques (MRI).
Lying or distorting the truth
Treatment begins with vitamin B1 (thiamine) supplements. These supplements are aimed at correcting the patient’s thiamine deficiency. Stopping or reducing alcohol consumption may stop the progression of the syndrome.
Psychotherapy and supportive treatments may be applied for persistent mental disorders such as Korsakoff psychosis
Thiamine Deficiency
Wernicke-Korsakoff Syndrome is a result of a major public health problem such as alcoholism. With early diagnosis and appropriate treatment, the quality of life of patients can be significantly improved. However, prevention of this syndrome is possible by controlling alcohol consumption and paying attention to the diet.