Krebs Cycle
The theory of abiogenesis, or its precursor the Oparin-Haldane hypothesis, suggests that life could spontaneously arise from simple chemical compounds. Studies in this context have shown that the Krebs cycle (also known as the citric acid cycle) can function under simple conditions through chemical reactions alone. This suggests that the basic metabolic processes of life could initiate through natural chemical processes, potentially laying the foundation for the evolution of more complex organisms.
It shows that it can also work under primitive Earth conditions
Scientists have taken a significant step in understanding the origins of life. A new study has demonstrated that the chemical processes at the beginning of life could function even without metals and enzymes. This discovery shows that the biochemical pathway known as the Krebs cycle, vital for energy production in all living organisms, could operate under primitive Earth conditions.
It suggests that life can spontaneously form from simple chemical compounds

Abiogenesis Theory
This theory is a fundamental concept for scientists trying to understand how life began and how complex organisms evolved. Abiogenesis explains how the first chemical processes at the beginning of life occur.
A Cycle That Works Without Metals and Enzymes
Recent research has revealed that the fundamental reactions of the Krebs cycle could occur under primitive Earth conditions without metals and enzymes. This finding suggests that chemical pathways that could produce energy may have existed at the beginning of life, even before the emergence of complex biochemical structures and enzymes.
It offers important clues about the chemical origin of life on primitive Earth
A Universal Process?
Researchers examined how the Krebs cycle might work with simple components by creating conditions similar to the early Earth’s atmosphere in a laboratory setting. This work proved that, using simple organic molecules and inorganic compounds, the fundamental reactions of the Krebs cycle can occur.
The Role of Metals and Enzymes
This discovery, which shows that the Krebs cycle can operate without metals and enzymes under primitive Earth conditions, makes an important contribution to the theory of abiogenesis. While these findings raise new questions about the beginning of life, they also provide a new perspective on existing theories. By continuing their research in this field, scientists will try to better understand the chemical origins and evolutionary process of life.